Sai Krishna, A V S;Ramu, Alagammai;Hariharan, Srimathangi;Sinha, Swati;Donakonda, Sainitin
Characterization of tumor microenvironment in glioblastoma multiforme identifies ITGB2 as a key immune and stromal related regulator in glial cell types.
Comput Biol Med
2023
165

Winkler, Frances;Hipp, Anna V;Ramirez, Carlos;Martin, Bianca;Villa, Matteo;Neuwirt, Emilia;Gorka, Oliver;Aerssens, Jeroen;Johansson, Susanne E;Rana, Nisha;Llewellyn-Lacey, Sian;Price, David A;Panning, Marcus;Groß, Olaf;Pearce, Erika L;Hermann, Carl M;Schumann, Kathrin;Hannibal, Luciana;Neumann-Haefelin, Christoph;Boettler, Tobias;Knolle, Percy;Hofmann, Maike;Wohlleber, Dirk;Thimme, Robert;Bengsch, Bertram
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+ T cells.
Gut
2023
72
10
1971-1984

Jayakumar, Manju Nidagodu;Muhammad, Jibran Sualeh;Dutta, Mainak;Donakonda, Sainitin
Comprehensive In silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic targets and their small-molecule inhibitors for the treatment of cholangiocarcinoma.
Comput Biol Med
2023
166

Pedde, A.;Baumann, T.;Kim, H.;Donakonda, S.;Bayerl, F.;Meiser, P.;Hirschberger, A.;Klement, C.;Grassmann, S.;Oellinger, R.;Flommersfeld, S.;Kirchhammer, N.;Trapani, J.;Smyth, M.;Hoechst, B.;Buchholz, V;Rad, R.;Sun, J.;Boettcher, J.
A dysfunctional program imprinted by Prostaglandin E2 signaling shuts off NK cell communication pathways and disables immunosurveillance of metastasis
Eur J Immunol
2023
53 Suppl 2
220-220

Meiser, P.;Knolle, M.;Hirschberger, A.;De Almeida, G.;Bayerl, F.;Lacher, S.;Pedde, A.;Flommersfeld, S.;Stoegbauer, F.;Anton, M.;Wirth, M.;Steiger, K.;Buchholz, V;Wollenberg, B.;Zielinski, C.;Braren, R.;Rueckert, D.;Knolle, P.;Kaissis, G.;Boettcher, J.
A distinct stimulatory cDC1 subpopulation amplifies CD8+T cell responses in tumors for protective anticancer immunity
Eur J Immunol
2023
53 Suppl 2
6-6

Lacher, S.;Doerr, J.;Almeida, G.;Hoenninger, J.;Meiser, P.;Bayerl, F.;Pedde, A.;Hirschberger, A.;Jarosch, S.;Gregor, L.;Busch, D.;Buchholz, V.;Knolle, P.;Zehn, D.;Kobold, S.;Boettcher, J.
Prostaglandin E2 curtails interleukin-2-dependent effector expansion from tumor-infiltrating stem-like CD8+T cells to promote cancer immune escape
Eur J Immunol
2023
53 Suppl 2
50-50

Bayerl, F.;Meiser, P.;Donakonda, S.;Hirschberger, A.;Lacher, S.;Pedde, A.;Hermann, C.;Elewaut, A.;Knolle, M.;Ramsauer, L.;Rudolph, T.;Grassmann, S.;Kirchhammer, N.;Trefny, M.;Zaremba, A.;Obenauf, A.;Zippelius, A.;Buchholz, V.;Schraml, B.;Boettcher, J.
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
Eur J Immunol
2023
53 Suppl 2
152-152

Griewahn, Laura;Müller-Foxworth, Madeleine;Peintner, Lukas;Wissler, Manuela;Weiss, Martina;Brauns-Schubert, Prisca;Massoumi, Ramin;Borner, Christoph;Groß, Olaf;Yabal, Monica;Charvet, Céline;Maurer, Ulrich
SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD.
Cell Rep
2023
42
1

Malfanti, Alessio;Sami, Haider;Balasso, Anna;Marostica, Giulia;Arpac, Busra;Mastrotto, Francesca;Mantovani, Giuseppe;Cola, Elisa;Anton, Martina;Caliceti, Paolo;Ogris, Manfred;Salmaso, Stefano
Control of cell penetration enhancer shielding and endosomal escape-kinetics crucial for efficient and biocompatible siRNA delivery.
J Control Release
2023
363
101-113

Bosch, Miriam;Kallin, Nina;Sainitin, Donakonda;Wintersteller, Hannah;Fuerst, Anna;Zhang, Jitao David;Ramirez, Carlos;Herrmann, Carl;Hofmann, Maike;Thimme, Robert;Protzer, Ulrike;Boettcher, Jan;Wohlleber, Dirk;Luangsay, Souphalone;Knolle, Percy A.
A PKA-associated liver-tissue rheostat curbs T cell receptor signalling and effector function of virus-specific CD8 T cells in chronic viral hepatitis
J Hepatol
2023
78 Suppl 1
S35-S35