Hitting the right button: MAVS-mediated defense against HAV infection.

Titel:: Hitting the right button: MAVS-mediated defense against HAV infection.
Dokumenttyp:: Journal Article
Autor(en):: Knolle, Percy A
Abstract:: Studying the immune response against infection with hepatitis viruses is hampered by the lack of suitable preclinical model systems. A recent publication in Science identifies the cytosolic adapter molecule MAVS as being responsible for species restriction of infection with hepatitis A virus as well as linking cytosolic immune sensing in infected hepatocytes with innate effector functions and protective adaptive immunity.
Zeitschriftentitel:: Cell Res
Jahr:: 2017
Band / Volume:: 27
Heft / Issue:: 1
Seitenangaben Beitrag:: 7-8
Sprache:: eng
Volltext / DOI:: doi:10.1038/cr.2016.139
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/27886168
Print-ISSN:: 1001-0602
TUM Einrichtung:: Roman Herzog Comprehensive Cancer Center
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