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Title:

Hitting the right button: MAVS-mediated defense against HAV infection.

Document type:
Journal Article
Author(s):
Knolle, Percy A
Abstract:
Studying the immune response against infection with hepatitis viruses is hampered by the lack of suitable preclinical model systems. A recent publication in Science identifies the cytosolic adapter molecule MAVS as being responsible for species restriction of infection with hepatitis A virus as well as linking cytosolic immune sensing in infected hepatocytes with innate effector functions and protective adaptive immunity.
Journal title abbreviation:
Cell Res
Year:
2017
Journal volume:
27
Journal issue:
1
Pages contribution:
7-8
Language:
eng
Fulltext / DOI:
doi:10.1038/cr.2016.139
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27886168
Print-ISSN:
1001-0602
TUM Institution:
Roman Herzog Comprehensive Cancer Center
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