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Title:

Diffusion Regulation in the Vitreous Humor

Document type:
Zeitschriftenaufsatz
Author(s):
Käsdorf, Benjamin Tillmann; Arends, Fabienna; Lieleg, Oliver
Abstract:
The efficient treatment of many ocular diseases depends on the rapid diffusive distribution of solutes such as drugs or drug delivery vehicles through the vitreous humor. However, this multicomponent hydrogel possesses selective permeability properties, which allow for the diffusion of certain molecules and particles, whereas others are immobilized. In this study, we perform an interspecies comparison showing that the selective permeability properties of the vitreous are conserved across several...     »
Keywords:
drug delivery, vitreous humor, hydrogel
Journal title:
Biophysical Journal
Year:
2015
Journal volume:
109
Journal issue:
10
Pages contribution:
2171-2181
Covered by:
Web of Science
Fulltext / DOI:
doi:10.1016/j.bpj.2015.10.002
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26588575
WWW:
http://www.cell.com/biophysj/supplemental/S0006-3495%2815%2901002-4
Publisher:
Elsevier BV
Print-ISSN:
0006-3495
Date of publication:
17.11.2015
TUM Institution:
MW Fachgebiet für Biomechanik am IMETUM
Ingested:
10.12.2015
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