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Title:

Characterization of all human male synaptonemal complexes by subtelomere multiplex-FISH

Author(s):
Codina-Pascual, M.; Kraus, J.; Speicher, M. R.; Oliver-Bonet, M.; Murcia, V.; Sarquella, J.; Egozcue, J.; Navarro, J.; Benet, J.
Abstract:
During meiotic prophase I, homologous chromosomes synapse and recombine. Both events are of vital importance for the success of meiosis. When homologous chromosomes synapse, a proteinaceous structure called synaptonemal complex (SC) appears along the pairing axis and meiotic recombination takes place. The existence of immunolabeling techniques for SC proteins (SCP1, SCP2 and SCP3) and for DNA mismatch repair proteins present in late recombination nodules (MLH1) allow analyses of both synapsis an...     »
Journal title:
Cytogenetic and Genome Research
Year:
2004
Journal volume:
107
Journal issue:
1-2
Pages contribution:
18--21
Fulltext / DOI:
doi:10.1159/000079566
Publisher:
S. Karger AG
Publisher address:
Basel, Switzerland
Print-ISSN:
1424859X
E-ISSN:
1424-859X
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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