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Title:

Chemotherapy-Induced Nausea and Vomiting in the Treatment of Gastrointestinal Tumors and Secondary Prophylaxis with Aprepitant

Author(s):
Abbrederis, Kathrin; Lorenzen, Sylvie; Rothling, Nadine; Ihbe-Heffinger, Angela; Schuster, Tibor; Peschel, Christian; Lordick, Florian
Abstract:
Background: Chemotherapy-induced nausea and vomiting (CINV) belongs to the most feared side-effects of cancer treatment. Its incidence during chemotherapy of gastrointestinal tu-mors (GITs) with highly and moderately emetogenic regimens is not well documented. It is also unknown whether aprepitant, a neurokinin-1 receptor antagonist, can be used as secondary antiemetic prophylaxis in case of CINV during cycle 1. Patients and Methods: Patients with GITs who were treated with highly and moderately...     »
Keywords:
Neurokinin-1 receptor; Chemotherapy-induced nausea and vomiting; Gastrointestinal tumors; Aprepitant
Journal title:
Onkologie
Year:
2009
Journal volume:
32
Journal issue:
1-2
Pages contribution:
30--34
Fulltext / DOI:
doi:10.1159/000183735
Publisher:
S. Karger GmbH
Publisher address:
Freiburg, Germany
Print-ISSN:
1423-0240
E-ISSN:
2296-5262
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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