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Titel:

Reproducibility of and Correspondence among Different Hepcidin Forms in Blood and Urine and Their Relationships to Iron Status in Healthy, Male Guatemalan Volunteers Observed over 9 Weeks

Autor(en):
Schuemann, Klaus; Solomons, Noel W.; Laarakkers, Coby M.; Romero-Abal, Mar'ia-Eugenia; Kroll, Sylvia; Weiss, Guenter; Swinkels, Dorine W.
Abstract:
Background/Aims: Prohepcidin and the active form hepcidin-25 are two variants of the peptide hormone hepcidin for iron homoeostasis. Their regulatory role and usefulness as biomarkers of the iron status are uncertain. Our aim is to describe the intra-individual variance of serum and urinary hepcidin-25 and prohepcidin concentrations, the mutual associations of the 4 hepcidin formats, and their correspondence with iron status variables in male Guatemalan volunteers. Methods: Eight healthy adult m...     »
Stichworte:
Hepcidin-25; Prohepcidin; Ferritin; Iron status; Iron regulation; Guatemala
Zeitschriftentitel:
Annals of Nutrition and Metabolism
Jahr:
2011
Band / Volume:
58
Heft / Issue:
2
Seitenangaben Beitrag:
158--166
Volltext / DOI:
doi:10.1159/000328657
Verlag / Institution:
S. Karger AG
Verlagsort:
Basel, Switzerland
Print-ISSN:
1421-9697
E-ISSN:
1421-9697
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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