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Titel:

12-week combined strength and endurance exercise attenuates CD8+ T-cell differentiation and affects the kynurenine pathway in the elderly: a randomized controlled trial

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Boßlau, Tim Konstantin; Wasserfurth, Paulina; Reichel, Thomas; Weyh, Christopher; Palmowski, Jana; Nebl, Josefine; Joisten, Niklas; Belen, Sergen; Schenk, Alexander; Hahn, Andreas; Zimmer, Philipp; Krüger, Karsten
Abstract:
Background: Age-related accumulation of highly differentiated CD8+ effector memory re-expressing CD45RA (EMRA) T-cells and disruption of the kynurenine (KYN) pathway are associated with chronic inflammation and the development of insulin resistance. In this study the aim was to investigate the effects of 12-week combined strength and endurance exercise on CD8+ T-cell differentiation and KYN pathway metabolites. Ninety-six elderly subjects (f/m, aged 50-70) were randomized to a control (CON) or e...     »
Dewey Dezimalklassifikation:
570 Biowissenschaften, Biologie; 610 Medizin und Gesundheit; 790 Sport, Spiele, Unterhaltung
Zeitschriftentitel:
Immunity & Ageing
Jahr:
2023
Band / Volume:
20
Heft / Issue:
1
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1186/s12979-023-00347-7
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37161540
Verlag / Institution:
Springer Science and Business Media LLC
E-ISSN:
1742-4933
Impact Factor:
7,9
Scimago-Quartil:
Q1
Eingereicht (bei Zeitschrift):
24.09.2022
Angenommen (von Zeitschrift):
03.05.2023
Publikationsdatum:
09.05.2023
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