Palladium-Catalyzed Direct 2-Alkylation of Indoles by Norbornene-Mediated Regioselective Cascade C-H Activation

Benutzer: Gast

Titel:: Palladium-Catalyzed Direct 2-Alkylation of Indoles by Norbornene-Mediated Regioselective Cascade C-H Activation
Dokumenttyp:: Journal Article
Autor(en):: Jiao, L.; Bach, T.
Abstract:: A palladium-catalyzed direct 2-alkylation reaction of free N-H indoles has been developed. This reaction relies on a norbornene-mediated cascade C-H activation process at the indole ring, which features high regioselectivity and excellent functional group, tolerance. The reaction represents the first example for a generally applicable, direct C-H alkylation of indole at the 2-position.
Kongresstitel:: ISI Document Delivery No.: 816IG Times Cited: 27 Cited Reference Count: 64 Jiao, Lei Bach, Thorsten Alexander von Humboldt foundation L.J. acknowledges support by the Alexander von Humboldt foundation. 27 Amer chemical soc Washington
Zeitschriftentitel:: Journal of the American Chemical Society
Jahr:: 2011
Band / Volume:: 133
Heft / Issue:: 33
Seitenangaben Beitrag:: 12990-12993
Volltext / DOI:: doi:10.1021/ja2055066
BibTeX