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Titel:

Serial profiling of cell-free DNA and nucleosome histone modifications in cell cultures.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Ungerer, Vida; Bronkhorst, Abel J; Van den Ackerveken, Priscilla; Herzog, Marielle; Holdenrieder, Stefan
Abstract:
Recent advances in basic research have unveiled several strategies for improving the sensitivity and specificity of cell-free DNA (cfDNA) based assays, which is a prerequisite for broadening its clinical use. Included among these strategies is leveraging knowledge of both the biogenesis and physico-chemical properties of cfDNA towards the identification of better disease-defining features and optimization of methods. While good progress has been made on this front, much of cfDNA biology remains...     »
Zeitschriftentitel:
Sci Rep
Jahr:
2021
Band / Volume:
11
Heft / Issue:
1
Volltext / DOI:
doi:10.1038/s41598-021-88866-5
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33947882
Print-ISSN:
2045-2322
TUM Einrichtung:
Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!)
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