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Titel:

Biodistribution and radiation dose estimates for Ga-DOTA-JR11 in patients with metastatic neuroendocrine tumors.

Dokumenttyp:
Journal Article
Autor(en):
Krebs, Simone; Pandit-Taskar, Neeta; Reidy, Diane; Beattie, Bradley J; Lyashchenko, Serge K; Lewis, Jason S; Bodei, Lisa; Weber, Wolfgang A; O'Donoghue, Joseph A
Abstract:
Somatostatin receptor antagonists have shown promise for imaging neuroendocrine tumors (NETs) in preclinical studies, but clinical data is still very limited. In this study, we assess the feasibility of using the novel somatostatin antagonist Ga-DOTA-JR11 for PET imaging of NETs.Twenty patients with advanced NETs underwent whole-body PET/CT imaging 60 min after injection of 169 MBq (median) Ga-DOTA-JR11 as part of a prospective study. Volumes of interest were drawn around up to four Ga-DOTA-JR11...     »
Zeitschriftentitel:
Eur J Nucl Med Mol Imaging
Jahr:
2019
Band / Volume:
46
Heft / Issue:
3
Seitenangaben Beitrag:
677-685
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00259-018-4193-y
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30374529
Print-ISSN:
1619-7070
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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