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- Title:
Racial Variations in Appetite-Related Hormones, Appetite, and Laboratory-Based Energy Intake from the E-MECHANIC Randomized Clinical Trial
- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Dorling, James L.; Church, Timothy S.; Myers, Candice A.; Höchsmann, Christoph; White, Ursula A.; Hsia, Daniel S.; Martin, Corby K.; Apolzan, John W.
- Abstract:
- African Americans (AAs) have a higher obesity risk than Whites; however, it is unclear if appetite-related hormones and food intake are implicated. We examined differences in appetite-related hormones, appetite, and food intake between AAs (n = 53) and Whites (n = 111) with overweight or obesity. Participants were randomized into a control group or into supervised, controlled exercise groups at 8 kcal/kg of body weight/week (KKW) or 20 KKW. Participants consumed lunch and dinner at baseline and follow-up, with appetite and hormones measured before and after meals (except leptin). At baseline, AAs had lower peptide YY (PYY; p < 0.01) and a blunted elevation in PYY after lunch (p = 0.01), as well as lower ghrelin (p = 0.02) and higher leptin (p < 0.01) compared to Whites. Despite desire to eat being lower and satisfaction being higher in AAs relative to Whites (p ≤ 0.03), no racial differences in food intake were observed. Compared to Whites, leptin increased in the 8 KKW group in AAs (p = 0.01), yet no other race-by-group interactions were evident. Differences in appetite-related hormones between AAs and Whites exist; however, their influence on racial disparities in appetite, food intake, and obesity within this trial was limited.
- Dewey Decimal Classification:
- 570 Biowissenschaften, Biologie; 610 Medizin und Gesundheit; 790 Sport, Spiele, Unterhaltung
- Journal title:
- Nutrients
- Year:
- 2019
- Journal volume:
- 11
- Journal issue:
- 9
- Pages contribution:
- 2018
- Reviewed:
- ja
- Language:
- en
- Fulltext / DOI:
- doi:10.3390/nu11092018
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/31466276
- Publisher:
- MDPI AG
- E-ISSN:
- 2072-6643
- Impact Factor:
- 6,706
- Scimago Quartil:
- Q1
- Submitted:
- 20.06.2019
- Accepted:
- 24.08.2019
- Date of publication:
- 28.08.2019
- Semester:
- SS 19
- TUM Institution:
- Professur für Bewegung, Ernährung und Gesundheit
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