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Original title:
Prävalenz und Prädiktoren für Upgrading und Upstaging bei Männern mit Low-Risk und Favorable-Intermediate-Risk Prostatakarzinom unter besonderer Berücksichtigung der onkologischen Familienanamnese
Translated title:
Prevalence and predictors of upgrading and upstaging in men with low-risk (LR) and favorable-intermediate-risk (FIR) prostate cancer (PCa), with focus on the oncological family history
Author:
Maier, Nikola Viktoria
Year:
2023
Document type:
Dissertation
Faculty/School:
TUM School of Medicine and Health
Advisor:
Herkommer, Kathleen (Prof. Dr.)
Referee:
Herkommer, Kathleen (Prof. Dr.); Heidegger, Simon (Priv.-Doz. Dr.)
Language:
de
Subject group:
MED Medizin
Keywords:
Prostatakarzinom, Upgrading, Upstaging
Translated keywords:
prostate cancer, upgrading, upstaging
TUM classification:
MED 500
Abstract:
Die Prävalenz von postoperativem Upgrading (Gleason-Score >=7b) und Upstaging (>=pT3a oder pN1) wurde an 4.091 zwischen 1994 und 2019 radikal prostatektomierten LR und FIR PCa-Patienten analysiert und mittels multipler Regressionen Prädiktoren hierfür identifiziert. Bei LR PCa hatten 7,2% ein Upgrading und 12,1% ein Upstaging. Bei FIR PCa hatten je nach Gleason-Score und PSA-Wert zwischen 10,6-13,8% ein Upgrading und 16,6-24,1% ein Upstaging. Ein erhöhtes Risiko für Upgrading bzw. Upstaging bei...     »
Translated abstract:
Prevalence for postoperative upgrading (Gleason-Score >=7b) and upstaging (>=pT3a or pN1) was analysed in 4,091 LR and FIR PCa-patients who underwent radical prostatectomy between 1994 and 2019. Predictors were identified using multiple regressions. In LR PCa, 7.2% had upgrading and 12.1% had upstaging. In FIR PCa, between 10.6-13.8% had upgrading and 16.6-24.1% had upstaging, depending on Gleason-Score and PSA level. Predictors for upgrading and upstaging in LR or FIR PCa were higher age, highe...     »
WWW:
https://mediatum.ub.tum.de/?id=1686244
Date of submission:
23.09.2022
Oral examination:
04.07.2023
File size:
1363134 bytes
Pages:
72
Urn (citeable URL):
https://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:91-diss-20230704-1686244-1-6
Last change:
15.12.2023
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