This thesis examines the incidence and distribution of spinal cord lesions in multiple sclerosis and analyses the correlation between spinal cord involvement and the progression of disability. For this purpose, T2-weighted MRI images of 588 patients and 30 healthy controls were segmented, lesion profiles for different clinical phenotypes created, and the correlation between EDSS scores and spinal and cerebral (lesion) volume, age, gender, and disease duration analyzed by a multiple linear regression model.
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This thesis examines the incidence and distribution of spinal cord lesions in multiple sclerosis and analyses the correlation between spinal cord involvement and the progression of disability. For this purpose, T2-weighted MRI images of 588 patients and 30 healthy controls were segmented, lesion profiles for different clinical phenotypes created, and the correlation between EDSS scores and spinal and cerebral (lesion) volume, age, gender, and disease duration analyzed by a multiple linear regres...
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