The purpose of this prospective study was to examine associations between „neutrophile gelatinase associated lipocalin“ (NGAL), a biomarker for the early prediction of acute kidney injury and the outcome as well as the preload in 107 critically ill patients. NGAL levels were significantly different in patients with normal, increased and decreased preload, measured as global enddiastolic volume index (GEDVI). High levels of NGAL were associated with mortality and the requirement of renal replacement therapy. The prospective value of NGAL exceeded serum creatinine and serum blood urea nitrogen at the time of admission to the intensive care unit.
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The purpose of this prospective study was to examine associations between „neutrophile gelatinase associated lipocalin“ (NGAL), a biomarker for the early prediction of acute kidney injury and the outcome as well as the preload in 107 critically ill patients. NGAL levels were significantly different in patients with normal, increased and decreased preload, measured as global enddiastolic volume index (GEDVI). High levels of NGAL were associated with mortality and the requirement of renal replace...
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