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- Original title:
- Eine retrospektive Analyse an Prostatakarzinom-Langzeitüberlebenden nach radikaler Prostatovesikulektomie unterschiedlicher Risikogruppen - Sind Prostatakarzinom-Patienten der intermediate-risk Gruppe auch für Active Surveillance geeignet?
- Translated title:
- A retrospective analysis of long-term prostate cancer survivors after radical prostatovesiculectomy of different risk groups - Are prostate cancer patients of the intermediate-risk group also candidates for Active Surveillanve?
- Author:
- Woll, Mira Magdalena
- Year:
- 2024
- Document type:
- Dissertation
- Faculty/School:
- TUM School of Medicine and Health
- Advisor:
- Herkommer, Kathleen (Prof. Dr.)
- Referee:
- Herkommer, Kathleen (Prof. Dr.); Thalgott, Mark (Priv.-Doz. Dr.)
- Language:
- de
- Subject group:
- MED Medizin
- TUM classification:
- MED 500
- Abstract:
- Active Surveillance (AS) als Therapieoption bei intermediate-risk (IR) Prostatakarzinom wird aktuell diskutiert. Bei 5.693 Patienten wurde das Langzeitüberleben potenzieller AS Kandidaten untersucht (medianes Follow-Up: 9,30 Jahre). In der low-risk und der favorable-IR Gruppe war das Überleben vergleichbar, in der unfavorable-IR Gruppe im Vergleich deutlich schlechter (p<0,001). Ungünstigere histopathologische Parameter wie die Tumorausbreitung und der Gleason-Score waren mit schlechterem Überleben assoziiert (p<0,05).
- Translated abstract:
- Active surveillance (AS) for intermediate-risk (IR) prostate cancer as a therapy option is currently being discussed. The long-term survival of potential AS candidates was investigated in 5,693 patients (median follow-up: 9,30 years). Survival was comparable in the low-risk and the favorable-IR group, but significantly worse in the unfavorable-IR group (p <0.001). Worse histopathological parameters such as tumor expansion and Gleason score were associated with worse survival (p <0.05).
- WWW:
- https://mediatum.ub.tum.de/?id=1712969
- Date of submission:
- 07.07.2023
- Oral examination:
- 19.01.2024
- File size:
- 3097083 bytes
- Pages:
- 79
- Urn (citeable URL):
- https://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:91-diss-20240119-1712969-1-0
- Last change:
- 19.02.2024
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