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Titel:

The Hippo signal transduction network in skeletal and cardiac muscle

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Wackerhage H, Del Re DP, Judson RN, Sudol M, Sadoshima J
Abstract:
The discovery of the Hippo pathway can be traced back to two areas of research. Genetic screens in fruit flies led to the identification of the Hippo pathway kinases and scaffolding proteins that function together to suppress cell proliferation and tumor growth. Independent research, often in the context of muscle biology, described Tead (TEA domain) transcription factors, which bind CATTCC DNA motifs to regulate gene expression. These two research areas were joined by the finding that the Hippo...     »
Dewey Dezimalklassifikation:
570 Biowissenschaften, Biologie; 610 Medizin und Gesundheit
Zeitschriftentitel:
Science Signaling
Jahr:
2014
Band / Volume:
7
Heft / Issue:
337
Sprache:
en
Volltext / DOI:
doi:10.1126/scisignal.2005096
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25097035
Verlag / Institution:
Science
E-ISSN:
1937-9145
Impact Factor:
6.4
TUM Einrichtung:
Sportbiologie
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