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Titel:

Can bone tissue engineering contribute to therapy concepts after resection of musculoskeletal sarcoma?

Dokumenttyp:
Journal Article
Autor(en):
Holzapfel, Boris Michael; Chhaya, Mohit Prashant; Melchels, Ferry Petrus Wilhelmus; Holzapfel, Nina Pauline; Prodinger, Peter Michael; von Eisenhart-Rothe, Ruediger; Van Griensven, Martijn; Schantz, Jan-Thorsten; Rudert, Maximilian; Hutmacher, Dietmar Werner
Abstract:
Resection of musculoskeletal sarcoma can result in large bone defects where regeneration is needed in a quantity far beyond the normal potential of self-healing. In many cases, these defects exhibit a limited intrinsic regenerative potential due to an adjuvant therapeutic regimen, seroma, or infection. Therefore, reconstruction of these defects is still one of the most demanding procedures in orthopaedic surgery. The constraints of common treatment strategies have triggered a need for new therap...     »
Zeitschriftentitel:
Sarcoma
Jahr:
2013
Band / Volume:
2013
Seitenangaben Beitrag:
153640
Sprache:
eng
Volltext / DOI:
doi:10.1155/2013/153640
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23509421
Print-ISSN:
1357-714X
TUM Einrichtung:
Klinik und Poliklinik für Orthopädie und Sportorthopädie; Klinik und Poliklinik für Unfallchirurgie; Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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