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Title:

Locating multiple interacting quantitative trait loci with the zero-inflated generalized Poisson regression

Document type:
Zeitschriftenaufsatz
Author(s):
Erhardt, V., Bogdan, M. and Czado, C.
Abstract:
We consider the problem of locating multiple interacting quantitative trait loci (QTL) influencing traits measured in counts. In many applications the distribution of the count variable has a spike at zero. Zero-inflated generalized Poisson regression (ZIGPR) allows for an additional probability mass at zero and hence an improvement in the detection of significant loci. Classical model selection criteria often overestimate the QTL number. Therefore, modified versions of the Bayesian Inform...     »
Journal title:
Statistical Applications in Genetics and Molecular Biology
Year:
2010
Journal volume:
9
Year / month:
2010-06
Journal issue:
1
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.2202/1544-6115.1545
Status:
Verlagsversion / published
Semester:
SS 10
TUM Institution:
Lehrstuhl für Mathematische Statistik
Format:
Text
 BibTeX