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Dokumenttyp:
Zeitschriftenaufsatz 
Autor(en):
Saez-Rodriguez, J.; Hammerle-Fickinger, A.; Dalal, O.; Klamt, S.; Gilles, E.D.; Conradi, C 
Titel:
Multistability of signal transduction motifs 
Abstract:
Protein domains are the basic units of signalling processes. The mechanisms they are involved in usually follow recurring patterns, such as phosphorylation/dephosphorylation cycles. A set of common motifs was defined and their dynamic models were analysed with respect to number and stability of steady states. In a first step, Feinberg’s chemical reaction network theory was used to determine whether a motif can show multistationarity or not. The analysis revealed that, apart from double-step acti...    »
 
Zeitschriftentitel:
IET Systems Biolology 
Jahr:
2008 
Band / Volume:
Heft / Issue:
(2) 
Seitenangaben Beitrag:
80-93 
Sprache:
en 
TUM Einrichtung:
Zentralinstitut für Ernährungs- und Lebensmittelforschung / Abteilung Physiologie 
Format:
Text