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Document type:
Zeitschriftenaufsatz 
Author(s):
Albrecht, C.; Viturro, E 
Title:
The ABCA subfamily – gene and protein structures, functions and associated hereditary diseases 
Abstract:
To date, 12 members of the human ABCA subfamily are identified. They share a high degree of sequence conservation and have been mostly related with lipid trafficking in a wide range of body locations. Mutations in some of these genes have been described to cause severe hereditary diseases related with lipid transport, such as fatal surfactant deficiency or harlequin ichthyosis. In addition, most of them are hypothesized to participate in the subcellular sequestration of drugs, thereby being resp...    »
 
Keywords:
ATP-binding cassette transporters; Lipid transport; Full-transporters; ABCA subfamily 
Journal title:
Pflügers Archiv: European Journal of Physiology 
Year:
2007 
Journal volume:
453: 
Pages contribution:
581-589 
Language:
en 
TUM Institution:
Zentralinstitut für Ernährungs- und Lebensmittelforschung / Abteilung Physiologie 
Format:
Text