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Document type:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't 
Author(s):
Meissner, Karin; Lutter, Dominik; von Toerne, Christine; Haile, Anja; Woods, Stephen C; Hoffmann, Verena; Ohmayer, Uli; Hauck, Stefanie M; Tschoep, Matthias H 
Title:
Molecular classification of the placebo effect in nausea. 
Abstract:
In this proof-of-concept study, we tested whether placebo effects can be monitored and predicted by plasma proteins. In a randomized controlled design, 90 participants were exposed to a nauseating stimulus on two separate days and were randomly allocated to placebo treatment or no treatment on the second day. Significant placebo effects on nausea, motion sickness, and (in females) gastric activity could be verified. Using label-free tandem mass spectrometry, 74 differentially regulated proteins...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2020 
Journal volume:
15 
Journal issue:
Print-ISSN:
1932-6203 
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)