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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Müller, Günter A; Tschöp, Matthias H; Müller, Timo D 
Title:
Upregulated phospholipase D activity toward glycosylphosphatidylinositol-anchored proteins in micelle-like serum complexes in metabolically deranged rats and humans. 
Abstract:
Glycosylphosphatidylinositol-anchored proteins (GPI-AP) with the complete glycolipid anchor attached have previously been shown to be released from the outer plasma membrane leaflet of rat adipocytes in positive correlation to cell size and blood glucose/insulin levels of the donor rats. Furthermore, they are present in rat and human serum, however, at amounts that are lower in insulin-resistant/obese rats compared with normal ones. These findings prompted further evaluation of the potential of...    »
 
Journal title abbreviation:
Am J Physiol Endocrinol Metab 
Year:
2020 
Journal volume:
318 
Journal issue:
Pages contribution:
E462-E479 
Print-ISSN:
0193-1849 
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)