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Document type:
Journal Article 
Author(s):
Heitmann, Henrik; Andlauer, Till F M; Korn, Thomas; Mühlau, Mark; Henningsen, Peter; Hemmer, Bernhard; Ploner, Markus 
Title:
Fatigue, depression, and pain in multiple sclerosis: How neuroinflammation translates into dysfunctional reward processing and anhedonic symptoms. 
Abstract:
Fatigue, depression, and pain affect the majority of multiple sclerosis (MS) patients, which causes a substantial burden to patients and society. The pathophysiology of these symptoms is not entirely clear, and current treatments are only partially effective. Clinically, these symptoms share signs of anhedonia, such as reduced motivation and a lack of positive affect. In the brain, they are associated with overlapping structural and functional alterations in areas involved in reward processing....    »
 
Journal title abbreviation:
Mult Scler 
Year:
2020 
Fulltext / DOI:
Print-ISSN:
1352-4585 
TUM Institution:
Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik