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Document type:
Journal Article; Review 
Author(s):
Hofmann, Franz 
Title:
The cGMP system: components and function. 
Abstract:
The cyclic guanosine monophosphate (cGMP) signaling system is one of the most prominent regulators of a variety of physiological and pathophysiological processes in many mammalian and non-mammalian tissues. Targeting this pathway by increasing cGMP levels has been a very successful approach in pharmacology as shown for nitrates, phosphodiesterase (PDE) inhibitors and stimulators of nitric oxide-guanylyl cyclase (NO-GC) and particulate GC (pGC). This is an introductory review to the cGMP signalin...    »
 
Journal title abbreviation:
Biol Chem 
Year:
2020 
Journal volume:
401 
Journal issue:
Pages contribution:
447-469 
Fulltext / DOI:
Print-ISSN:
1431-6730 
TUM Institution:
Institut für Pharmakologie und Toxikologie