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Document type:
Journal Article; Review 
Author(s):
Vornholz, Larsen; Ruland, Jürgen 
Title:
Physiological and Pathological Functions of CARD9 Signaling in the Innate Immune System. 
Abstract:
Caspase recruitment domain protein 9 (CARD9) forms essential signaling complexes in the innate immune system that integrate cues from C-type lectin receptors and specific intracellular pattern recognition receptors. These CARD9-mediated signals are pivotal for host defense against fungi, and they mediate immunity against certain bacteria, viruses and parasites. Furthermore, CARD9-regulated pathways are involved in sterile inflammatory responses critical for immune homeostasis and can control pro...    »
 
Journal title abbreviation:
Curr Top Microbiol Immunol 
Year:
2020 
Journal volume:
429 
Pages contribution:
177-203 
Fulltext / DOI:
Print-ISSN:
0070-217X 
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie