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Dokumenttyp:
Zeitschriftenaufsatz 
Autor(en):
Marczynski, Matthias; Balzer, Bizan N.; Jiang, Kun; Lutz, Theresa M.; Crouzier, Thomas; Lieleg, Oliver 
Titel:
Charged glycan residues critically contribute to the adsorption and lubricity of mucins 
Abstract:
In the human body, mucin glycoproteins efficiently reduce friction between tissues and thereby protect the mucosa from mechanical damage. Mucin lubricity is closely related to their molecular structure: it has been demonstrated previously that the hydrophobic termini of mucins critically contribute to their lubricity. If and how intrinsic sources of negative charge in mucins, e.g., sulfated glycans and sialic acid residues, are relevant for the tribological behavior of mucin solutions has, howev...    »
 
Stichworte:
Adsorption, AFM, DNA, Lubricity, Mucin, QCM-D, Sialic acid, Sulfate, Tribology 
Dewey Dezimalklassifikation:
500 Naturwissenschaften 
Zeitschriftentitel:
Colloids and Surfaces B: Biointerfaces 
Jahr:
2020 
Band / Volume:
187 
Seitenangaben Beitrag:
110614 
Nachgewiesen in:
Scopus 
Reviewed:
ja 
Sprache:
en 
Verlag / Institution:
Elsevier BV 
E-ISSN:
0927-7765 
Publikationsdatum:
01.03.2020 
TUM Einrichtung:
Fachgebiet für Biomechanik