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Document type:
Zeitschriftenaufsatz 
Author(s):
Thon, M.P., Ford, H.Z., Gee, M.W., Myerscough, M.R. 
Title:
A Quantitative Model of Early Atherosclerotic Plaques Parameterized Using In Vitro Experiments 
Abstract:
There is a growing number of studies that model immunological processes in the artery wall that lead to the development of atherosclerotic plaques. However, few of these models use parameters that are obtained from experimental data even though data-driven models are vital if mathematical models are to become clinically relevant. We present the development and analysis of a quantitative mathematical model for the coupled inflammatory, lipid and macrophage dynamics in early atherosclerotic pla...    »
 
Keywords:
atherosclerosis, plaque development, quantitative model, parameter estimation, metabolic control analysis, stability analysis 
Journal title:
Bulletin of Mathematical Biology 
Year:
2018 
Covered by:
Scopus 
Notes:
This is a pre-print of an article published in Bulletin of Mathematical Biology. The final authenticated version is available online at: https://doi.org/10.1007/s11538-017-0367-1 
Status:
Verlagsversion / published