Mechanical ventilation can cause severe lung damage by inadequate adjustment of the ventilator. We introduce a Machine Learning approach to predict the pressure-dependent, non-linear lung compliance, a crucial parameter to estimate lung protective ventilation settings. Features were extracted by fitting a generally accepted lumped parameter model to time series data obtained from ARDS (adult respiratory distress syndrome) patients. Numerical prediction was performed by use of Gaussian processes, a probabilistic, non-parametric modeling approach for non-linear functions.     «

Mechanical ventilation can cause severe lung damage by inadequate adjustment of the ventilator. We introduce a Machine Learning approach to predict the pressure-dependent, non-linear lung compliance, a crucial parameter to estimate lung protective ventilation settings. Features were extracted by fitting a generally accepted lumped parameter model to time series data obtained from ARDS (adult respiratory distress syndrome) patients. Numerical prediction was performed by use of Gaussian processes,...     »