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Dokumenttyp:
journal article 
Autor(en):
Schneider, L; Hartwig, W; Flemming, T; Hackert, T; Fortunato, F; Heck, M; Gebhard, MM; Nawroth, PP; Bierhaus, A; Buchler, MW; Werner, J 
Titel:
Protective effects and anti-inflammatory pathways of exogenous calcitonin gene-related peptide in severe necrotizing pancreatitis. 
Abstract:
BACKGROUND: Microcirculatory disturbances are known to play a pivotal role in the pathogenesis of severe necrotizing pancreatitis (SNP). Calcitonin gene-related peptide (CGRP) is a vasodilatatory neuropeptide with potential anti-inflammatory effects. This study characterizes the protective effects and the anti-inflammatory pathway of exogenous CGRP in SNP. METHODS: SNP was induced in rats using the glycodeoxycholic acid model. CGRP was injected prophylactically before or therapeutically after in...    »
 
Zeitschriftentitel:
Pancreatology 
Jahr:
2009 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
662-9 
Sprache:
eng 
Print-ISSN:
1424-3903 
TUM Einrichtung:
Urologische Klinik und Poliklinik