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Document type:
journal article 
Author(s):
Kleppisch, T; Feil, R 
Title:
cGMP signalling in the mammalian brain: role in synaptic plasticity and behaviour. 
Abstract:
The second messenger cyclic guanosine 3',5'-monophosphate (cGMP) plays a crucial role in the control of cardiovascular and gastrointestinal homeostastis, but its effects on neuronal functions are less established. This review summarizes recent biochemical and functional data on the role of the cGMP signalling pathway in the mammalian brain, with a focus on the regulation of synaptic plasticity, learning, and other complex behaviours. Expression profiling, along with pharmacological and genetic m...    »
 
Journal title abbreviation:
Handb Exp Pharmacol 
Year:
2009 
Journal issue:
191 
Pages contribution:
549-79 
Language:
eng 
Print-ISSN:
0171-2004 
TUM Institution:
Institut für Pharmakologie und Toxikologie