Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Ahles, A; Engelhardt, S 
Titel:
Polymorphisms determine beta-adrenoceptor conformation: implications for cardiovascular disease and therapy. 
Abstract:
Beta(1)- and beta(2)-adrenoceptors are crucial regulators of cardiovascular function. Agonists and antagonists at these receptor subtypes are cornerstones in the treatment of cardiovascular disease. In humans, both of the genes encoding the beta(1)- and beta(2)-adrenoceptors carry frequent polymorphisms resulting in different variants of the receptor proteins. Whether the polymorphic nature of the receptors causes the clinically observed differences with respect to the response of the patients t...    »
 
Zeitschriftentitel:
Trends Pharmacol Sci 
Jahr:
2009 
Band / Volume:
30 
Heft / Issue:
Seitenangaben Beitrag:
188-93 
Sprache:
eng 
Print-ISSN:
0165-6147 
TUM Einrichtung:
r Pharmakologie und Toxikologie