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Dokumenttyp:
journal article 
Autor(en):
Reim, D; Westenfelder, K; Kaiser-Moore, S; Schlautkötter, S; Holzmann, B; Weighardt, H 
Titel:
Role of T cells for cytokine production and outcome in a model of acute septic peritonitis. 
Abstract:
Although it is generally accepted that early defense mechanisms are controlled by cells of the innate immune system, T cells were found to be crucial for host resistance against acute septic peritonitis. However, the mechanisms by which T cells mediate protection are not fully understood. Here, we demonstrate mice deficient for recombinase-activating gene (RAG) 1, which lack mature B and T cells, showed enhanced susceptibility and impaired bacterial clearance in a model of acute septic peritonit...    »
 
Zeitschriftentitel:
Shock 
Jahr:
2009 
Band / Volume:
31 
Heft / Issue:
Seitenangaben Beitrag:
245-50 
Sprache:
eng 
Print-ISSN:
1073-2322 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; Urologische Klinik und Poliklinik