Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Schaaf, C; Shan, B; Buchfelder, M; Losa, M; Kreutzer, J; Rachinger, W; Stalla, GK; Schilling, T; Arzt, E; Perone, MJ; Renner, U 
Titel:
Curcumin acts as anti-tumorigenic and hormone-suppressive agent in murine and human pituitary tumour cells in vitro and in vivo. 
Abstract:
Curcumin (diferuloylmethane) is the active ingredient of the spice plant Curcuma longa and has been shown to act anti-tumorigenic in different types of tumours. Therefore, we have studied its effect in pituitary tumour cell lines and adenomas. Proliferation of lactosomatotroph GH3 and somatotroph MtT/S rat pituitary cells as well as of corticotroph AtT20 mouse pituitary cells was inhibited by curcumin in monolayer cell culture and in colony formation assay in soft agar. Fluorescence-activated ce...    »
 
Zeitschriftentitel:
Endocr Relat Cancer 
Jahr:
2009 
Band / Volume:
16 
Heft / Issue:
Seitenangaben Beitrag:
1339-50 
Sprache:
eng 
Print-ISSN:
1351-0088 
TUM Einrichtung:
Neurochirurgische Klinik und Poliklinik