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Document type:
journal article 
Author(s):
Baumann, M; Janssen, BJ; Rob Hermans, JJ; Bartholome, R; Smits, JF; Struijkerboudier, HA 
Title:
Renal medullary effects of transient prehypertensive treatment in young spontaneously hypertensive rats. 
Abstract:
AIM: Transient angiotensin II receptor blockade (ARB) leads to prolonged blood pressure (BP) lowering, but the underlying mechanism remains uncertain. Long-term BP control is regulated by the medullary microcirculation with the pericyte as contractile cell. We hypothesize that the prolonged BP effect is caused by increased medullary blood flow (MBF) associated with structural alterations based on reduced medullary pericyte number. METHODS: Four-week-old spontaneously hypertensive rats (SHR) were...    »
 
Journal title abbreviation:
Acta Physiol (Oxf) 
Year:
2009 
Journal volume:
196 
Journal issue:
Pages contribution:
231-7 
Language:
eng 
Print-ISSN:
1748-1708 
TUM Institution:
Abteilung für Nephrologie