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Dokumenttyp:
journal article 
Autor(en):
Antoniou, AC; Sinilnikova, OM; McGuffog, L; Healey, S; Nevanlinna, H; Heikkinen, T; Simard, J; Spurdle, AB; Beesley, J; Chen, X; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer; Neuhausen, SL; Ding, YC; Couch, FJ; Wang, X; Fredericksen, Z; Peterlongo, P; Peissel, B; Bonanni, B; Viel, A; Bernard, L; Radice, P; Szabo, CI; Foretova, L; Zikan, M; Claes, K; Greene, MH; Mai, PL; Rennert, G; Lejbkowicz, F; Andrulis, IL; Ozcelik, H; Glendon, G; OCGN; Gerdes, AM; Thomass...    »
 
Titel:
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. 
Abstract:
Genome-wide association studies of breast cancer have identified multiple single nucleotide polymorphisms (SNPs) that are associated with increased breast cancer risks in the general population. In a previous study, we demonstrated that the minor alleles at three of these SNPs, in FGFR2, TNRC9 and MAP3K1, also confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. Three additional SNPs rs3817198 at LSP1, rs13387042 at 2q35 and rs13281615 at 8q24 have since been reported to...    »
 
Zeitschriftentitel:
Hum Mol Genet 
Jahr:
2009 
Band / Volume:
18 
Heft / Issue:
22 
Seitenangaben Beitrag:
4442-56 
Sprache:
eng 
Print-ISSN:
0964-6906 
TUM Einrichtung:
Frauenklinik und Poliklinik