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Dokumenttyp:
journal article 
Autor(en):
Shephard, ND; Abo, R; Rigas, SH; Frank, B; Lin, WY; Brock, IW; Shippen, A; Balasubramanian, SP; Reed, MW; Bartram, CR; Meindl, A; Schmutzler, RK; Engel, C; Burwinkel, B; Cannon-Albright, LA; Allen-Brady, K; Camp, NJ; Cox, A 
Titel:
A breast cancer risk haplotype in the caspase-8 gene. 
Abstract:
Recent large-scale studies have been successful in identifying common, low-penetrance variants associated with common cancers. One such variant in the caspase-8 (CASP8) gene, D302H (rs1045485), has been confirmed to be associated with breast cancer risk, although the functional effect of this polymorphism (if any) is not yet clear. In order to further map the CASP8 gene with respect to breast cancer susceptibility, we performed extensive haplotype analyses using single nucleotide polymorphisms (...    »
 
Zeitschriftentitel:
Cancer Res 
Jahr:
2009 
Band / Volume:
69 
Heft / Issue:
Seitenangaben Beitrag:
2724-8 
Sprache:
eng 
Print-ISSN:
0008-5472 
TUM Einrichtung:
Frauenklinik und Poliklinik