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Dokumenttyp:
journal article 
Autor(en):
Schottelius, M; Laufer, B; Kessler, H; Wester, HJ 
Titel:
Ligands for mapping alphavbeta3-integrin expression in vivo. 
Abstract:
The alpha(v)beta(3)- and alpha(5)beta(1)-integrins play a key role in angiogenesis, the formation of new vessels in tissues that lack them. By serving as receptors for a variety of extracellular matrix proteins containing an arginine-glycine-aspartic acid (RGD) sequence, these integrins mediate migration of endothelial cells into the basement membrane and regulate their growth, survival, and differentiation. Besides being involved in angiogenesis, the alpha(v)beta(3)-integrin is also presented o...    »
 
Zeitschriftentitel:
Acc Chem Res 
Jahr:
2009 
Band / Volume:
42 
Heft / Issue:
Seitenangaben Beitrag:
969-80 
Sprache:
eng 
Print-ISSN:
0001-4842 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik