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Dokumenttyp:
journal article 
Autor(en):
Robel, S; Mori, T; Zoubaa, S; Schlegel, J; Sirko, S; Faissner, A; Goebbels, S; Dimou, L; Götz, M 
Titel:
Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis. 
Abstract:
Astrocytes play many pivotal roles in the adult brain, including their reaction to injury. A hallmark of astrocytes is the contact of their endfeet with the basement membrane surrounding blood vessels, but still relatively little is known about the signaling mediated at the contact site. Here, we examine the role of beta1-integrin at this interface by its conditional deletion using different Cre lines. Thereby, the protein was reduced only at postnatal stages either in both glia and neurons or s...    »
 
Zeitschriftentitel:
Glia 
Jahr:
2009 
Band / Volume:
57 
Heft / Issue:
15 
Seitenangaben Beitrag:
1630-47 
Sprache:
eng 
Print-ISSN:
0894-1491 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie