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Document type:
journal article 
Author(s):
Hartmann, O; Spyratos, F; Harbeck, N; Dietrich, D; Fassbender, A; Schmitt, M; Eppenberger-Castori, S; Vuaroqueaux, V; Lerebours, F; Welzel, K; Maier, S; Plum, A; Niemann, S; Foekens, JA; Lesche, R; Martens, JW 
Title:
DNA methylation markers predict outcome in node-positive, estrogen receptor-positive breast cancer with adjuvant anthracycline-based chemotherapy. 
Abstract:
PURPOSE: We have shown that DNA methylation of the PITX2 gene predicts risk of distant recurrence in steroid hormone receptor-positive, node-negative breast cancer. Here, we present results from a multicenter study investigating whether PITX2 and other candidate DNA methylation markers predict outcome in node-positive, estrogen receptor-positive, HER-2-negative breast cancer patients who received adjuvant anthracycline-based chemotherapy. EXPERIMENTAL DESIGN: Using a microarray platform, we anal...    »
 
Journal title abbreviation:
Clin Cancer Res 
Year:
2009 
Journal volume:
15 
Journal issue:
Pages contribution:
315-23 
Language:
eng 
Print-ISSN:
1078-0432 
TUM Institution:
Frauenklinik und Poliklinik