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Dokumenttyp:
journal article 
Autor(en):
Martinez-Torres, F; Menon, S; Pritsch, M; Victor, N; Jenetzky, E; Jensen, K; Schielke, E; Schmutzhard, E; de Gans, J; Chung, CH; Luntz, S; Hacke, W; Meyding-Lamadé, U; GACHE Investigators 
Titel:
Protocol for German trial of Acyclovir and corticosteroids in Herpes-simplex-virus-encephalitis (GACHE): a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial [ISRCTN45122933]. 
Abstract:
BACKGROUND: The treatment of Herpes-simplex-virus-encephalitis (HSVE) remains a major unsolved problem in Neurology. Current gold standard for therapy is acyclovir, a drug that inhibits viral replication. Despite antiviral treatment, mortality remains up to 15%, less than 20% of patients are able to go back to work, and the majority of patients suffer from severe disability. This is a discouraging, unsatisfactory situation for treating physicians, the disabled patients and their families, and co...    »
 
Zeitschriftentitel:
BMC Neurol 
Jahr:
2008 
Band / Volume:
Seitenangaben Beitrag:
40 
Sprache:
eng 
TUM Einrichtung:
Neurologische Klinik und Poliklinik