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Dokumenttyp:
journal article 
Autor(en):
Tencer, L; Burgermeister, E; Ebert, MP; Liscovitch, M 
Titel:
Rosiglitazone induces caveolin-1 by PPARgamma-dependent and PPRE-independent mechanisms: the role of EGF receptor signaling and its effect on cancer cell drug resistance. 
Abstract:
BACKGROUND: Caveolin-1, a key component of plasma membrane caveolae, has been implicated in the regulation of cancer cell growth and survival. Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a ligand-activated nuclear receptor which plays a pivotal role in many cellular processes. Activation of PPARgamma by its ligand rosiglitazone upregulates caveolin-1 mRNA and protein in human carcinoma cells. MATERIALS AND METHODS: We have used specific signaling inhibitors to dissect the mec...    »
 
Zeitschriftentitel:
Anticancer Res 
Jahr:
2008 
Band / Volume:
28 
Heft / Issue:
2A 
Seitenangaben Beitrag:
895-906 
Sprache:
eng 
Print-ISSN:
0250-7005 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik