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Document type:
journal article 
Author(s):
Fekete, A; Rosta, K; Wagner, L; Prokai, A; Degrell, P; Ruzicska, E; Vegh, E; Toth, M; Ronai, K; Rusai, K; Somogyi, A; Tulassay, T; Szabo, AJ; Ver, A 
Title:
Na+,K+-ATPase is modulated by angiotensin II in diabetic rat kidney--another reason for diabetic nephropathy? 
Abstract:
Angiotensin II (ANGII) plays a central role in the enhanced sodium reabsorption in early type 1 diabetes in man and in streptozotocin-induced (STZ) diabetic rats. This study investigates the effect of untreated STZ-diabetes leading to diabetic nephropathy in combination with ANGII treatment, on the abundance and localization of the renal Na(+),K(+)-ATPase (NKA), a major contributor of renal sodium handling. After 7 weeks of STZ-diabetes (i.v. 65 mg kg(-1)) a subgroup of control (C) and diabetic...    »
 
Journal title abbreviation:
J Physiol 
Year:
2008 
Journal volume:
586 
Journal issue:
Pt 22 
Pages contribution:
5337-48 
Language:
eng 
Print-ISSN:
0022-3751 
TUM Institution:
Abteilung für Nephrologie