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Dokumenttyp:
journal article 
Autor(en):
Heit, A; Busch, DH; Wagner, H; Schmitz, F 
Titel:
Vaccine protocols for enhanced immunogenicity of exogenous antigens. 
Abstract:
Vaccination protocols aim at the delivery of exogenous antigen (Ag) to antigen-presenting cells (APCs) concurrent with the activation of APCs by adjuvants. Activated APCs then cross-present the Ag, cross-prime T effector cells, and activate B cells. Classical protocols rely on a mixture of both Ag and the adjuvant. However, a disadvantage of this strategy is that simultaneous "loading" and activation of APCs is not guaranteed. As a consequence, heterogeneous APC populations will be generated, in...    »
 
Zeitschriftentitel:
Int J Med Microbiol 
Jahr:
2008 
Band / Volume:
298 
Heft / Issue:
1-2 
Seitenangaben Beitrag:
27-32 
Sprache:
eng 
Print-ISSN:
1438-4221 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene