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Dokumenttyp:
journal article 
Autor(en):
Steppich, BA; Seitz, I; Busch, G; Stein, A; Ott, I 
Titel:
Modulation of tissue factor and tissue factor pathway inhibitor-1 by neutrophil proteases. 
Abstract:
During systemic inflammation, neutrophil activation is accompanied by endothelial cell damage and hypercoagulability. Activated neutrophils release serine proteases that participate in tissue injury. We sought to investigate the effects of neutrophil proteases on proinflammatory and procoagulant changes in endothelial cells. The effects of elastase (HNE), cathepsin G (CG), and proteinase 3 (PR3) on expression of tissue factor (TF) and tissue factor pathway inhibitor-1 (TFPI) were examined in hum...    »
 
Zeitschriftentitel:
Thromb Haemost 
Jahr:
2008 
Band / Volume:
100 
Heft / Issue:
Seitenangaben Beitrag:
1068-75 
Sprache:
eng 
Print-ISSN:
0340-6245 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik