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Document type:
journal article 
Author(s):
Hofling, SB; Hultsch, C; Wester, HJ; Heinrich, MR 
Title:
Radiochemical F-18-fluoroarylation of unsaturated alpha-, beta- and gamma-amino acids, application to a radiolabelled analogue of baclofen 
Abstract:
Unsaturated alpha-, beta- and gamma-amino acids have been investigated as substrates for the reductive Meerwein arylation. Radical reactions of this type have been shown to be a valuable tool for the fast and efficient introduction of the 4-[F-18]fluorophenyl group into precursor molecules allowing short-time syntheses of potential PET radiotracers, which would be more difficult to access by other methods. (C) 2008 Elsevier Ltd. All rights reserved. 
Journal title abbreviation:
Tetrahedron 
Year:
2008 
Journal volume:
64 
Journal issue:
52 
Pages contribution:
11846-11851 
Language:
eng 
Print-ISSN:
0040-4020 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik