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Document type:
journal article 
Author(s):
Arnold, D; Höhler, T; Dittrich, C; Lordick, F; Seufferlein, T; Riemann, J; Wöll, E; Herrmann, T; Zubel, A; Schmoll, HJ 
Title:
Cetuximab in combination with weekly 5-fluorouracil/folinic acid and oxaliplatin (FUFOX) in untreated patients with advanced colorectal cancer: a phase Ib/II study of the AIO GI Group. 
Abstract:
BACKGROUND: This two-part phase Ib/II study investigated the feasibility of administering cetuximab in combination with oxaliplatin and infusional 5-fluorouracil (5-FU)/folinic acid (FA) in a weekly schedule (AIO FUFOX protocol) as first-line treatment in patients with epidermal growth factor receptor-detectable advanced colorectal cancer. PATIENTS AND METHODS: Cetuximab was administered weekly: 400 mg/m(2) initial dose, then 250 mg/m(2) and FUFOX: oxaliplatin 50 mg/m(2), FA 500 mg/m(2) and 5-FU...    »
 
Journal title abbreviation:
Ann Oncol 
Year:
2008 
Journal volume:
19 
Journal issue:
Pages contribution:
1442-9 
Language:
eng 
Print-ISSN:
0923-7534 
TUM Institution:
III. Medizinische Klinik und Poliklinik