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Dokumenttyp:
journal article 
Autor(en):
Lordick, F; Ott, K; Weitz, J; Jäger, D 
Titel:
The evolving role of catumaxomab in gastric cancer. 
Abstract:
BACKGROUND: Gastric cancer is a condition with a high medical need. Even after R0 resection the rate of peritoneal and other distant site recurrences is high. Novel therapeutic approaches include trifunctional antibodies (trAb) that recruit and activate different types of immune effector cells at the tumour site. The trAb catumaxomab has dual antigen specificity for epithelial cell adhesion molecule and CD3 and binds to Fcgamma-receptor-positive accessory cells. Intraperitoneal administration of...    »
 
Zeitschriftentitel:
Expert Opin Biol Ther 
Jahr:
2008 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
1407-15 
Sprache:
eng 
Print-ISSN:
1471-2598 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik