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Document type:
journal article 
Author(s):
Lordick, F; Ott, K; Weitz, J; Jäger, D 
Title:
The evolving role of catumaxomab in gastric cancer. 
Abstract:
BACKGROUND: Gastric cancer is a condition with a high medical need. Even after R0 resection the rate of peritoneal and other distant site recurrences is high. Novel therapeutic approaches include trifunctional antibodies (trAb) that recruit and activate different types of immune effector cells at the tumour site. The trAb catumaxomab has dual antigen specificity for epithelial cell adhesion molecule and CD3 and binds to Fcgamma-receptor-positive accessory cells. Intraperitoneal administration of...    »
 
Journal title abbreviation:
Expert Opin Biol Ther 
Year:
2008 
Journal volume:
Journal issue:
Pages contribution:
1407-15 
Language:
eng 
Print-ISSN:
1471-2598 
TUM Institution:
III. Medizinische Klinik und Poliklinik