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Dokumenttyp:
journal article 
Autor(en):
Schweneker, M; Favre, D; Martin, JN; Deeks, SG; McCune, JM 
Titel:
HIV-induced changes in T cell signaling pathways. 
Abstract:
Infection with HIV usually results in chronic activation of the immune system, with profound quantitative and qualitative changes in the T cell compartment. To better understand the mechanistic basis for T cell dysfunction and to discern whether such mechanisms are reversed after effective antiviral treatment, we analyzed changes in signaling pathways of human CD4(+) and CD8(+) T cells from 57 HIV-infected subjects in varying stages of disease progression and treatment, including long-term nonpr...    »
 
Zeitschriftentitel:
J Immunol 
Jahr:
2008 
Band / Volume:
180 
Heft / Issue:
10 
Seitenangaben Beitrag:
6490-500 
Sprache:
eng 
Print-ISSN:
0022-1767 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik