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Document type:
journal article 
Author(s):
Schweneker, M; Favre, D; Martin, JN; Deeks, SG; McCune, JM 
Title:
HIV-induced changes in T cell signaling pathways. 
Abstract:
Infection with HIV usually results in chronic activation of the immune system, with profound quantitative and qualitative changes in the T cell compartment. To better understand the mechanistic basis for T cell dysfunction and to discern whether such mechanisms are reversed after effective antiviral treatment, we analyzed changes in signaling pathways of human CD4(+) and CD8(+) T cells from 57 HIV-infected subjects in varying stages of disease progression and treatment, including long-term nonpr...    »
 
Journal title abbreviation:
J Immunol 
Year:
2008 
Journal volume:
180 
Journal issue:
10 
Pages contribution:
6490-500 
Language:
eng 
Print-ISSN:
0022-1767 
TUM Institution:
III. Medizinische Klinik und Poliklinik