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Dokumenttyp:
journal article 
Autor(en):
Kiechle, M; Arnold, N; Schlegelberger, B 
Titel:
Hereditary ovarian carcinoma 
Abstract:
Approximately 8000 women are diagnosed with epithelial ovarian carcinoma in Germany every year, making it the second most common genital malignancy. It comes seventh in cause-of-death statistics, thus assuming a prominent place among gynaecological tumours. Of these tumours, 95% occur sporadically. In 5%-10% of cases, a genetic predisposition is assumed. Ovarian carcinoma belongs to the genital malignancies which carry a poor prognosis. Germline mutations in the BRCA1 and BRCA2 genes are respons...    »
 
Zeitschriftentitel:
Onkologe 
Jahr:
2008 
Band / Volume:
14 
Heft / Issue:
11 
Seitenangaben Beitrag:
1120-+ 
Sprache:
eng 
Print-ISSN:
0947-8965 
TUM Einrichtung:
Frauenklinik und Poliklinik