User: Guest  Login
Document type:
journal article 
Author(s):
Kiechle, M; Arnold, N; Schlegelberger, B 
Title:
Hereditary ovarian carcinoma 
Abstract:
Approximately 8000 women are diagnosed with epithelial ovarian carcinoma in Germany every year, making it the second most common genital malignancy. It comes seventh in cause-of-death statistics, thus assuming a prominent place among gynaecological tumours. Of these tumours, 95% occur sporadically. In 5%-10% of cases, a genetic predisposition is assumed. Ovarian carcinoma belongs to the genital malignancies which carry a poor prognosis. Germline mutations in the BRCA1 and BRCA2 genes are respons...    »
 
Journal title abbreviation:
Onkologe 
Year:
2008 
Journal volume:
14 
Journal issue:
11 
Pages contribution:
1120-+ 
Language:
eng 
Print-ISSN:
0947-8965 
TUM Institution:
Frauenklinik und Poliklinik